The MRC Centre for Regenerative Medicine (CRM) is a world leading research centre based at the University of Edinburgh. Together we study stem cells, disease and tissue repair to advance human health. Our research is aimed at developing new treatments for major diseases including cancer, heart disease, diabetes, degenerative diseases such as multiple sclerosis and Parkinson's disease, and liver failure. The Centre houses 26 research groups and has a staff of more than 230 scientists, graduate students, support and ancillary staff. Our work is currently organised into five themes. To promote collaboration within the Centre, we adopt a flexible approach to these themes with each Principal Investigator (PI) having one or more secondary affiliations. Two themes focus on fundamental research: pluripotency and IPS, and lineage and cell specification. The other three aim to translate fundamental research discoveries into clinical programmes relevant to brain, blood and liver diseases and to tissue repair. The Centre has strong collaborative links to other centres within the University, such as the Euan MacDonald Centre for MND Research, the MS Centre and the Roslin Institute.