The Centre for Integrative Physiology (CIP) fosters research into fundamental mechanisms and pathways relevant to human function and disease. CIP investigators exploit rapid advances in the enabling technologies available from genomics, proteomics, imaging, informatics, and in vivo analysis to understand the function of gene products at the cell, organ and whole-animal level. Importantly, CIP investigators exploit the most appropriate model organisms/systems to investigate the key physiological question being posed: a delicate balance between high biomedical relevance (for example human, mouse, rat) and high genetic power (such as Drosophila and fish).